Breast cysts present as smooth, non-tender masses. They will often disappear over the course of the menstrual cycle, but those that persist will need further evaluation.

Cyst aspiration is frequently attempted, using a small needle and syringe.

After aspiration of the cyst fluid is performed primarily to confirm the fact of the cyst and to decompress it. Many physicians discard the cyst fluid unless it is bloody as cyst fluid cytologic examination is felt to be of little value.

Following decompression of the cyst, the patient returns for periodic follow-up to look for recurrence. Recurrent cysts in the same location are often subjected to excisional biopsy or fine needle aspiration biopsy.