Birth Control
Pills
Benefits of BCPs
Note to readers from
the Brookside Associates:
Although this page faithfully
reproduces the original Operational Medicine 2001, there is a
better (updated, with pictures) version of it in
Military Obstetrics & Gynecology. |
BCPs provide highly reliable contraceptive protection, exceeding 99%.
Even when imperfect use (skipping an occasional pill) is considered, the BCPs are still
very effective in preventing pregnancy.
In addition to their contraceptive benefits, the BCPs have a number of
other benefits. BCPs generally:
- Cause menstrual cycles to occur regularly and predictably
- Shorten menstrual flows
- Lighten menstrual flows
- Reduce the risk of iron deficiency anemia
- Reduce menstrual cramps
- Eliminate painful ovulation
- Reduce premenstrual symptoms
- Reduce cyclic breast pain
- Improve acne
- Reduce the risk of ovarian cysts
- Reduce the risk of ovarian cancer
- Reduce the risk of uterine cancer
- Reduce the risk of uterine fibroid tumors
- Reduce the risk of symptomatic endometriosis
- Reduce the risk of pelvic inflammatory disease
- Reduce the risk of benign breast disease
Risks of BCPs
Aside from a number of minor, but annoying, side effects, serious risks
of BCPs are limited, for the most part, to cardiovascular problems, including stroke,
heart attack, thrombophlebitis and thromboembolism.
- These complications are very rare among women under age 35 who
are non-smokers, and the added risk of BCPs is difficult to measure and probably
insignificant.
- For non-smokers over age 35, the increased risk of
cardiovascular problems among BCP users is measurable, but extremely small and certainly
less than the risk of pregnancy.
- For smokers under age 35, the increased risk of
cardiovascular problems among BCP users is measurable, but extremely small and certainly
less than the risk of pregnancy.
- For smokers over age 35, the increased risk of
cardiovascular problems among BCP users is very significant, and so high as to make such
use ill-advised in any but the most extraordinary circumstances.
There is also a very small, but measurable increase in the risk of liver
tumors and cysts. The incidence of such problems in the population is so small and the
added risk so marginal that only rarely will this risk play a role in the clinical
decision for or against BCPs .
Which Pill to Start
Pick any standard, low-dose birth control pill that is readily
available.
Most women (90%) will do well on any low-dose BCP. A few will do well
only on certain BCPs, but there is no way to predict in advance which pill will work best
for any individual woman.
Historically, as the hormone dose of birth control pills was lowered,
the risk of serious complications such as blood clots was also reduced. For that reason,
starting a low-dose pill (30-35 mcg of estrogen) is preferable to starting medium dose (50
mcg) or high dose BCPs. Lowering the dose below the 30-35 mcg dose has not, however, led
to any additional clinical benefits but has made some of the very-low-dose pills more
"unforgiving" than the standard low-dose BCPs.
Starting the Pill
Take the first pill on the first Sunday following the beginning of the menstrual
flow.
This means that if a period starts on a Tuesday, you should wait all the way through
the week until Sunday, and then start taking the BCPs. If the period starts on a Saturday,
then the first BCP would be taken the next day, Sunday. If the period starts on a Sunday,
take the BCPs the same day. This method is called a "Sunday Start" and has a
number of advantages. Because a fresh pill pack is always started on Sunday, it is easier
for some people to remember. Using a "Sunday Start" means that the pill-induced
periods will usually begin early in the week (Monday or Tuesday) and will be over before
the weekend. Many women find this timing convenient and desirable.
An alternative method ("5th Day") is to always start the BCP pack on day #5
of the menstrual cycle. Day #1 is the first day of flow. This method is very effective but
requires counting and recalculations each month.
When are the Pills Effective?
The pills are reasonably effective right away.
Some physicians recommend that women use a back-up method of
contraception (such as condoms) during the first month of BCP use.This is based on the
observation that BCPs probably do not achieve their 99.9% effectiveness until after the
first month of use.
It is also true that the BCPs are pretty effective, even starting with
the first BCP. Many BCP manufacturers suggest that the BCP is effective after 7 days of
continuous use. Even before 7 days of BCPs have been taken, considering that phase of the
menstrual cycle, pregnancy is not very likely. For these reasons, the BCPs are probably
about as effective as using a diaphragm (~85%-95% effective) as soon as they are started.
For women seeking a higher level of protection against pregnancy (99.9%), using a backup
method of contraception during the first month of BCP use may be considered.
Skipped a Pill
If she just skipped one pill, she should take it as soon as she remembers, then
continue the rest of the pills at the normal time.
If she didn't remember until the next day, take both the current day's pill and
yesterday's pill together. Then continue with the rest of the pills in the usual way.
If she's forgotten two pills or more, stop the BCPs, wait a few days for a
"withdrawal" menstrual flow, and then restart a fresh package of BCPs 5 days
after the onset of flow. Use backup contraception during this time and for the first month
after restarting the BCPs.
History of Migraine Headaches
A history of migraine headaches is not a contra-indication to taking
birth control pills.
Some women with migraine headaches find they have fewer headaches while
taking BCPs. This is particularly true for those women whose headaches primarily occur
with ovulation or around the time of the menstrual flow. Other women with migraine
headaches find the BCPs have no noticeable effect on their headache frequency or severity.
These women may safely take BCPs.
Those women who experience worsening of their migraine headaches should
not be continue the same BCP. Switching to a different pill, with different content, from
a different manufacturer, may solve the problem. If not, it will generally be necessary to
stop the BCP completely.
High Blood Pressure
The birth control pill may be safely prescribed to women with
pre-existing high blood pressure, but it is important for many reasons that the blood
pressure be monitored and well-controlled.
BCPs occasionally aggravate pre-existing high blood pressure. If this
happens, switching to a different pill will sometimes solve the problem. If switching
fails to resolve the problem, then usually the BCP will need to be stopped.
BCPs will rarely cause a woman with normal blood pressure to become
hypertensive. If this happens, switching to a different pill manufacturer will often solve
the problem, but if not, the BCP is usually stopped.
Diabetes
The birth control pill may be safely taken by women with either a
personal history or family history of diabetes melitus.
Women who have diabetes often find taking BCPs has either no effect on
their diabetic control or else improves their control. Some women find they need more
insulin while taking BCPs, but are otherwise satisfied with the pill and these women may
safely take it. A few women find their diabetic control is adversely affected by the BCP.
For those women, changing the pill may be tried, but often the BCP must be discontinued.
Women with a family history of diabetes generally have no trouble taking
BCPs. Very rarely, the BCPs may provoke diabetes (or unmask it). If this happens,
alternative BCPs may be tried but usually the BCPs will be discontinued.
Blood Clot History
Women who have personally experienced such blood clot problems as
deep-vein thrombophlebitis, pulmonary embolism, cerebrovascular accident (stroke) or heart
attack should not, under ordinary circumstances, take birth control pills.
Women who have a family history of such problems but who have not,
personally, experienced the problems, may safely take BCPs.
The Particular Pill She's Using is not
Available
Switch her to a BCP that is available.
This is frequently an issue in operational settings. Because medical
resources are not unlimited in these situations, it is often necessary to switch to a
different pill. Since most women (90%) will tolerate any BCP without difficulty,
making a switch is usually uneventful and most women will not notice any difference. It is
best to make the switch at the time the old pills would have been started (after the
"off" week), but they can be switched at any time during the cycle.
It is possible but not common that they will experience some of the
side-effects of nausea, spotting or breast tenderness during the first month of the
switch. After the first month of the switch, these symptoms generally disappear.
Anticipate that some of these women will be reluctant to change pills,
particularly if they have had good success with one pill for a long time or if they had
difficulty finding a pill that worked well for them.
Postponing a Period with BCPs
If a woman is expected to have a menstrual period at a time that is
inconvenient or troublesome from an operational standpoint, it is often possible to
postpone the menstrual flow using BCPs.
Usually, BCPs inhibit ovulation and menstrual periods occur among women
taking BCPs only because the user stops taking the BCPs for a few days. The fall in
hormone levels triggers an apparently "normal" menstrual flow.
With that principle in mind, a woman's normal menstrual flow can often
be postponed by starting BCPs within 5 days of the beginning of her last menstrual flow.
When she comes to the end of a 21-day pack of BCPs, she goes immediately into the next
pack of BCPs (skipping the "week off.") She then continues with the second
pack until such time as it becomes convenient to have a menstrual flow. Stopping the pills
at this time will provoke a normal flow about 3 days after stopping the pills.
This use of pills will usually keep her from ovulating (and keep her
from having a period at the normal time). It is safe and will not cause any other
disruption to the menstrual flow.
Postponing menstrual periods is a technique often used by women entering
short-term operational settings when they do not wish to have a menstrual flow while
operationally deployed. There are drawbacks, however, to this approach. While most women
tolerate BCPs without side-effects, some women (~20%) will experience such side effects as
breast tenderness, nausea and spotting. Most of these side effects will occur during the
first month of BCP usage. So a woman who takes BCPs for 6 weeks to postpone a menstrual
period may be substituting one nuisance (menses at an inopportune time) for another
nuisance (nausea, breast tenderness, spotting). One way to avoid these problems is to
begin the BCPs well enough in advance of the operational commitment that any minor side
effects have worn off.
Another issue to consider is that while BCPs usually inhibit ovulation,
they don't always inhibit ovulation. In other words, this
menstrual-flow-postponing-protocol may not work, although it usually does.
Choose a monophasic, standard low-dose BCP, such as LoOvral, Ortho
Novum 1+35, LoEstrin 1.5/30 or similar pill
when using it for this purpose. Avoid multiphasic pills and extremely low dose pills as
their inhibition of ovulation is less reliable although they certainly are effective as
far as contraception is concerned.
Read more about continuous BCPs
Side Effects
Most women (about 80%) experience no side effects while taking BCPs.
The rest experience generally minor side-effects during the first month
of BCPs. These side-effects might include breast tenderness, nausea, spotting or
headaches, and generally disappear after the first month. If they persist, changing to a
different pill, from a different manufacturer, with different hormonal content, will
usually eliminate the problem.
Occasionally, several pills will need to be tried before the best (least
side effect for that individual person) is found. Very rarely, no satisfactory BCP can be
found and those women will need to make a judgment whether they would rather continue the
BCPs (with the side effect but with the BCP benefits) or to use an alternative method of
contraception.
Breast Tenderness
Breast tenderness is relatively common during the first month of BCPs and uncommon
thereafter.
Persistent breast tenderness is most often associated with fibrocystic breasts.
Typically, women with this condition notice the breast tenderness getting much worse just
before menses and much better after the onset of flow. BCPs are a reasonably effective
treatment for fibrocystic breasts so subsequent development of significant breast pain
should be viewed as unusual.
A careful breast exam should be done to rule out newly-developed breast disease. A
recent onset of significant breast tenderness should raise your suspicions about a
possible unsuspected pregnancy.
Nausea
Nausea occurring after the 1st month or severe nausea at any time should make you
suspicious of pregnancy, and this is usually ruled out by a negative pregnancy test or
convincing patient history.
Weight Gain
As individuals age, there is a tendency to gain weight, with or without BCPs. It is
difficult to show any significant additional weight gain in groups of women taking
low-dose BCPs compared to groups of women (of the same age) not taking BCPs.
That said, there are certainly individual women who gain weight when they take BCPs and
lose the weight when they stop taking the BCPs. Similarly, there are individual women who
lose weight while taking the BCPs and gain it back when they stop.
Headaches
While headaches can have many different causes, it is uncommon for the
birth control pill to provoke headaches.
Migraine headaches generally improve or stay the
same on BCPs, but occasionally get worse.
Premenstrual or menstrual headaches generally improve on BCPs, but
occasionally get worse. If a woman complains of headaches only during the "off
week" of BCPs, you can frequently resolve her headaches by modifying the way in which
she takes her BCPs. These menstrual headaches are often provoked by the withdrawal of
estrogen and progestin that accompanies the stopping of the BCPs at the end of each cycle.
- One way to resolve this problem is to shorten the "off week"
from seven days to three days. The three days off is enough to provoke a menstrual flow,
but about the time the hormone levels are low enough to provoke a headache, the woman
restarts a fresh pack of BCPs.
- Another way to resolve this problem is to eliminate the "off
week" entirely. A woman would go directly from one pack of pills into the next,
skipping the placebo pills or the "off week." She won't have a menstrual flow
and won't get menstrual headaches. After several months of this, she may experience some
breakthrough bleeding which can be safely ignored if occasional. If she bleeds every day,
then the BCPs can be stopped for 3 days to provoke a period and then restarted
continuously for another few months. Medically, this is equivalent to taking the BCPs in
the normal fashion, but avoids or minimizes the problem of menstrual headaches.
If headaches persist on the BCPs and alternative formulations or dosage
schedules fail to resolve the problem, the BCPs will generally be stopped.
Moodiness or Depression
Most cases of mood change are unrelated to the BCP use, but mood changes
are a recognized potential side effect.
In these cases, switching to a different BCP from a different
manufacturer, with a different hormone formulation, will often resolve this problem. If
the mood changes persist, it may be worthwhile to stop the BCPs for a month or two to see
if this resolves the problem.
Women with pre-existing depression, with or without anti-depression
medication, can safely take BCPs, but should be monitored for signs of worsening of their
depression.
It is not healthy to remain moody or depressed for long periods of time,
so this is an issue that clearly will need resolution one way or another.
Vaginal Dryness
Vaginal dryness or decreased lubrication during sexual activities is an
uncommon but not rare side effect.
This occurs when the BCP suppresses ovarian function (and natural
estrogen production) but does not replace enough estrogen (from the BCP) to fully
stimulate the vaginal and vulvar tissues. Women with this problem complain of vaginal
dryness, irritation, sometimes painful intercourse and diminished lubrication during sex.
Stopping the BCP will resolve this problem, but switching to a different
pill from a different manufacturer may also resolve the problem. Adding additional
estrogen (such as Premarin 0.625 daily)
can also be effective, but long-term use may pose added cardiovascular risks such as is
seen in the medium-dose or high-dose BCPs. "Personal Lubricants" can be used to
overcome the problem, such as Lubrin, Replense, or KY Jelly.
Decreased Libido (Sex-Drive)
Some women notice diminished interest in sex while taking BCPs.
Changing to a different BCP from a different manufacturer may resolve
this problem, but some of these women find that no matter what brand of BCP they take,
they experience this problem.
There are many possible causes of decreased libido, including stress and
relationship problems. To be certain the cause is the BCPs requires stopping the BCPs for
a reasonable period of time (1-3 months) and seeing if the libido returns. Then, the BCPs
are restarted to see if libido again changes.
Painful Menstrual Cramps
This is an unusual complaint for someone taking the birth control pill.
Usually, BCPs make menstrual cramps better and many women find they have
no cramps at all while taking BCPs. For someone to notice worsening of menstrual cramps
while taking BCPs suggests that some other medical problem has developed, such as pelvic
infection or endometriosis.
In an operational environment, it is may be worthwhile to obtain
cervical cultures for chlamydia and gonorrhea, but many physicians would give a course of
antibiotics considering the varying degrees of reliability of such cultures and unusual
nature of the symptoms in such circumstances. Good choices for antibiotics in this
situation would include any of the following:
The symptoms of menstrual cramps (dysmenorrhea) on BCPs can usually be relieved by
taking the BCPs continuously, without stopping for the "off week."
Whenever the operational commitment is complete, gynecologic consultation can be very
useful to look for the many causes of cyclic pelvic pain.
Continuous Birth Control Pills
In some operational settings, it may be desirable to avoid menstrual
flows completely. Depending on the tactical situation, changing sanitary pads or tampons
can be difficult, distracting or dangerous. Women with significant menstrual symptoms
(cramps, malaise, depression) may find it easier to complete their mission if menstruation
is avoided altogether.
Normally, women take BCPs for 3 weeks and then stop the BCPs for a week.
During the "off week," they have their menstrual period. The reason they have a
menstrual flow at that particular time is because they stopped taking the BCPs. In other
words, the menstrual flow is really a hormone withdrawal bleed. If they didn't stop taking
their BCPs, they wouldn't have a period.
Using this principle, a woman can go directly from one pack of pills
into the next, skipping the "week off." She won't have a period. At the end of
the second pack of pills, she can again go directly into the third pack, skipping the
"week off' and skipping a menstrual flow.
This way of taking BCPs is safe and just as effective in preventing
pregnancy as taking them the normal way. The only drawback is that she loses the regular,
monthly feedback of a menstrual flow, reassuring her that she is not pregnant. In
practice, the BCPs are so powerfully effective that effectiveness is not really an issue.
Should a woman become pregnant despite the use of BCPs (very, very rare), she will have
other symptoms suggesting the pregnancy, including breast tenderness, fatigue, nausea and
bloating.
In theory, women could use continuous BCPs indefinitely and never have a
period so long as she continued taking the pills. Actually, there are two limiting factors
to this approach. First, most women taking continuous BCPs will eventually experience some
spotting or breakthrough bleeding. If it is mild and occasional, it is generally ignored.
If it is daily or heavy, you can:
- Stop the BCPs for 3 days, provoking a period (withdrawal flow), and then
resume continuous BCPs until the spotting once again becomes annoying.
- Add a small amount of estrogen (Premarin 0.625/day, Estrace 1.0/day, etc.) to each BCP. This additional
estrogen will stimulate the uterine lining to become a little thicker and less fragile.
- Add any non-steroidal anti-inflammatory agents (NSAID) with significant
anti-prostaglandin activity. This will reduce the force of the normal, physiologic uterine
contractions and reduce or eliminate the spotting.
Second, some women will occasionally experience a break-through
ovulation, followed two weeks later by a menstrual flow. BCPs normally suppress ovulation,
but their contraceptive effectiveness does not depend totally on ovulation inhibition.
BCPs also change cervical mucous, fallopian tube motility, endometrial receptivity and
doubtlessly has other effects. Particularly with low-dose BCPs, some women will ovulate
anyway, although it is usually not noticed (when it occurs in phase with the BCP's), and
pregnancy does not occur. For women taking continuous BCPs, any ovulation will inevitably
be followed 2 weeks later by a full menstrual flow (whether she's taking BCPs or not), and
such an event will certainly be noticed. If the woman taking continuous BCPs has a
full-blown period, then it is wise to change to a different pill from a different
manufacturer. Monophasic pills work better for this purpose than multiphasic pills.
No Period or Very Light Period
The heaviness of a menstrual flow depends on the thickness of the lining of the uterus
just before the onset of menses. The thicker the lining, the heavier the flow. In women
using low-dose BCPs (for example: Ortho
Novum 1+35, LoOvral, Ovcon 35, etc.), there is a tendency for the uterine
lining to become very thin, over the course of many months.
Clinically, this is reflected as lighter and lighter periods which may even stop
completely.
This is not a dangerous condition and will resolve if the BCPs are stopped. Stopping
the BCPs is not necessary, however, because there are other safe alternatives. If the
periods are simply very light (1-2 days), you can ignore the problem because this
situation poses no threat to the patient.
If periods have totally stopped:
- Rule out pregnancy.
- You may change to a different BCP with different hormone in it. This will often lead to
recognizable periods because the different hormone is metabolized differently.
- You may add estrogen (Premarin .625 mg
or Estrace 1 mg) to each BCP to increase the
estrogen stimulation of the uterine lining, increasing its' thickness and leading to
heavier periods. After the desired effect has been achieved (recognizable periods), the
extra estrogen can be stopped.
- You may safely reassure the patient and allow her to remain without periods while taking
the BCPs. As long as she otherwise feels well, the absence of periods while taking BCPs is
not known to have any adverse effects and some women prefer to avoid monthly flows.
Spotting Between Periods
This symptom is common during the first month of BCPs, particularly with some of the
multiphasic BCPs.
This is not a dangerous condition, but may be a nuisance to the patient. In the
presence of a normal Pap smear, this symptom can be safely ignored for two months and more
likely than not, it will go away.
If spotting persists, changing to fixed-dose, mono-phasic BCP (such as Ortho Novum 1/35 or LoOvral) will usually solve the problem, particularly if
you switch to a different manufacturer.
Occasionally, women spot even following this change and these women should stop the BCP
briefly to make sure this symptom goes away. So long as the spotting disappears with
discontinuation of the BCP, you can safely conclude that the spotting was due to the BCP
and you may resume the BCP if you like. The spotting may return, but poses no threat.
Other benign conditions can cause spotting, such as endocervical or endometrial polyps,
cervical irritation, and uterine fibroid tumors, but none of these pose an immediate
threat and can reasonably be ignored for months if necessary until definitive gynecologic
consultation can be obtained.
Uterine malignancy in a woman under 35 is extremely rare, particularly if that woman
has been on BCPs. Spotting caused by uterine malignancy won't go away if BCPs are
discontinued. Cervical malignancy can be reasonably excluded by a recent (within 1 year)
normal Pap smear and the absence of a visible lesion on the cervix. Vaginal cancer
(extremely rare) is ruled out by a normal vaginal exam.
Periods at the Wrong Time
If a full menstrual flow occurs while the woman is taking her pills, this usually means
she has ovulated despite the BCPs.
This doesn't mean she will become pregnant, since the BCP has a number of ways of
preventing pregnancy in addition to inhibiting ovulation, but it may increase slightly the
statistical chance of pregnancy.
If she continues to take the same BCP according to her usual routine, the BCP may, over
the next month or two, achieve reasonable control over the menstrual cycle. Backup methods
of contraception should be employed during this time.
Alternatively, many gynecologists will stop the BCPs for 1-2 months to allow the
woman's normal cycle to re-assert itself, and then resume BCPs (but from a different
manufacturer, often using monophasic rather than multi-phasic BCPs) in step with the
woman's own cycle. This means starting the BCP the 5th day after the beginning of flow, or
alternatively, the first Sunday after the onset of the flow.
Pregnancy may also cause bleeding during the pill cycle.
Other causes for episodic abnormal bleeding include uterine fibroid tumors, uterine
polyps, trauma and malignancy. A physical exam will reveal some of these but others will
require more sophisticated gynecologic evaluation. Remember, uterine malignancy under age
35 is very rare and vaginal malignancy is extraordinarily rare. Cervical malignancy in the
presence of a normal Pap smear is also very uncommon.
If abnormal bleeding persists, gynecologic consultation will be necessary, but this can
be safely accomplished within weeks to months so long as the:
- patient is not bleeding heavily and continuously
- examination is normal
- Pap smear is within 1 year
- patient is less than 35 years old
Antibiotics
When taking Birth Control Pills and antibiotics, it is generally not necessary to use
any form of back-up contraception.
Taking antibiotics may lead to altered intestinal flora and ultimately to changed
levels of hormone in the patient's blood stream. This observation has led some authorities
to suggest the use of back-up contraception, believing that the changed levels of hormone
might diminish the effectiveness of the BCP.
In controlled studies, this theory has not been proven, and in the case of tetracycline and chlortetracycline, no increased risk of
pregnancy was found.
If taking antibiotics has any effect at all on pregnancy rates, the effect must be very
small and is not likely to have much clinical relevance in an operational setting.
Thinks She May be Pregnant
You should find out.
BCPs are the most effective reversible method of contraception and failures are
uncommon. Factors which increase the likelihood of failure would include skipping BCPs or
taking an interfering drug. Pregnancies may rarely occur in women taking the BCP
correctly.
Any time any woman taking BCPs thinks she might be pregnant, get a sensitive pregnancy
test. Usually, she'll be wrong and not pregnant, but occasionally, she'll be right and in
such cases the BCP should be immediately stopped.
Emergency Contraception ("Morning
After" Contraception)
Within 72 hours of unprotected intercourse, birth control pills can be
taken in such a way as to reduce the likelihood of pregnancy occurring.
Two Ovral (not LoOvral) are taken, followed 12 hours later by two more Ovral pills. No additional pills are taken. Should Ovral not be available, good alternatives include:
- LoOvral (four pills initially,
followed by four more, 12 hours later)
- Nordette (four pills initially,
followed by four more, 12 hours later)
- Levlen (four pills initially,
followed by four more, 12 hours later)
- Triphasil (four pills initially,
followed by four more, 12 hours later)
- Trilevelen (four pills initially,
followed by four more, 12 hours later)
If none of these pills are available, it is likely that any standard
low-dose BCP (four pills initially, followed by four more, 12 hours later) will have
similar effects. These other preparations have not been studied in as much depth, however,
so it is certainly preferable to use one of the listed BCPs.
With the use of emergency contraception, the risk of a pregnancy
occurring is reduced by about 75%. If 100 women have a single episode of unprotected
intercourse during the middle two weeks of their menstrual cycle, normally about 8 of them
will conceive. If they all use emergency contraception, only about 2 of them will
conceive, a 75% reduction in risk of pregnancy.
The greatest experience with emergency contraception has been within the
72-hour window. Some studies find emergency contraception is most effective the sooner it
is initiated within that 72 hours. Other studies find no difference in pregnancy rates. A
few studies have looked at the use of emergency contraception for up to 120 hours after
unprotected intercourse and find that it can still be effective in some cases, even after
72 hours.
The menstrual cycle is usually unaffected by the use of emergency
contraception. Breast tenderness is variable. Significant nausea occurs in about half of
women and vomiting affects in about one in 6 women. These symptoms generally disappear
within a day or two and can be moderated by using any standard anti-emetic or anti-nausea
drug starting an hour before the BCPs are taken. If started after the onset of symptoms,
these medications are not likely to be effective.
The mechanisms by which this contraceptive effect occurs have not been
established, but should a pregnancy occur despite the use of these BCPs, there is no
evidence of harm to the fetus from having been exposed.
Contraindications to use of emergency contraception are essentially the
same as those for use of the birth control pill in general. Previous stroke, undiagnosed
uterine bleeding, heart attack, deep vein thrombophlebitis and cancer of the breast or
uterus are all contraindications to sustained pill use. The extent to which they represent
risks in the context of emergency contraception is not known, but should be weighed in
evaluating a patient for emergency contraceptive use.
Overdose
A single overdose of BCPs is not likely to cause any serious harm.
Nausea, breast tenderness, and possibly a BCP withdrawal bleed (menstrual flow or
spotting) are possibilities if large numbers of BCPs are taken all at once. Gastric lavage
or induced vomiting are unnecessary.
If the overdose was accidental, consideration of alternative methods of
contraception can be explored, particularly those requiring less individual attention to
detail.
If the overdose was intentional, psychiatric evaluation is important as
other, more threatening attempts at self-harm may follow.
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