Erythromycin
(Ery-Tab, E-Mycin, Eryc)
Category:
Description:
Indications:
-
Upper
respiratory tract infections (S.
pyogenes, S. pneumoniae, H. inlfuenzae)
-
Lower
respiratory tract infections (S.
pyogenes, S. pneumoniae)
-
Respiratory
tract infections (Mycoplasma
pneumoniae)
-
Skin
infections (S. aureus, S.
pyogenes)
-
Pertussis
(Bordetella pertussis)
-
Diphtheria
(Corynebacterium diphtheriae)
-
Erythasma
(C. minutissimum)
-
Intestinal
amebiasis (Entamoeba histolytica)
-
Pelvic
inflammatory disease (N.
gonorrhoeae)
-
Conjunctivitis
(Chlamydia trachomatis)
-
Uncomplicated
urethral, endocervical or rectal infections (Chlamydia
trachomatis)
-
Nongonococcal
urethritis (Ureaplasma
urealyticum)
-
Primary
syphilis (Treponema pallidum)
-
Legionnaire’s
disease (Legionella pneumonphila)
-
Rheumatic
fever
-
Bacterial
endocarditis
-
Listeria monocytogenes infections
-
Unlabled
uses: Treponema pallidum,
Campylobacter jejuni, Lymphogranuloma vernereum, Calymmatobacterium
granulomatis, Haemophilus ducreyi (chanchroid)
Contraindications:
Precautions:
-
Pregnancy
category B
-
Counsel
patient to finish all medication to prevent development of resistance
-
Do
not use with cisapride (ventricular arrythmias w/macrolides)
-
Optimal
serum levels are achieved if taken in fasting state or immediately
before meals (base and stearate formulations). Ehtylsuccinate,estolate and enteric-coated erythromycin
formulations may be administered without regard for meals.
-
Urine
alkalinization (pH 8.5) increases gram-negative antibacterial
activity. If needed, administer with sodium bicarbonate or other
alkalinizing agent
-
Dosages
are expressed in the form of erythromycin base:
-
Erythromycin
Ethylsuccinate 400mg = 250mg of erythromycin base
Adverse
Reactions (Side Effects):
-
Hypersensitivity
-
Gastrointestinal:
abdominal pain (7.5%), nausea, vomiting, diarrhea (7.3%)
-
Headache
(8.2%)
-
Decreased
platelet count (4.8%)
-
Vaginitis
|
Dosage:
|
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Distribution is unlimited. The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks.
Source: Operational Medicine 2001, Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300.
Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300 |
Operational Medicine
Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
January 1, 2001 |
United States Special Operations
Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323 |
*This web version is provided by The Brookside Associates, LLC. It contains
original contents from the official US Navy NAVMED P-5139, but has been
reformatted for web access and includes advertising and links that were not
present in the original version. The medical information presented was reviewed and felt to be accurate in 2001. Medical knowledge and practice methods may have changed since that time. Some links may no longer be active. This web version has not been approved by the
Department of the Navy or the Department of Defense. The presence of any
advertising on these pages does not constitute an endorsement of that product or
service by either the US Department of Defense or the Brookside Associates. The
Brookside Associates is a private organization, not affiliated with the United
States Department of Defense.
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