OB-GYN 101
Pharmacy

Category:

• Analgesic

Description:

• Opiate agonist analgesic

Indications:

• Severe, acute pain

• Moderate to severe chronic pain

• Anesthesia adjunct for preoperative sedation

Contraindications:

• Patients with impaired respiratory function.

Precautions:

• Pregnancy Category C

• In patients with myocardial infarction, morphine decreases systemic vascular resistance which may lead to severe hypotension.  To minimize, administer minimum effective dose and elevate patient’s legs.

• Rapid administration may induce respiratory depression, therefore monitor patient’s respiratory function.

• Patients will experience CNS effects of drowsiness and dizziness, therefore use caution with motor vehicle operation or other hazardous tasks.

• Avoid prolonged, sustained usage to decrease addiction potential.

• Use with caution with other CNS depressive medications.

Adverse Reactions (Side Effects):

• Sedation

• Dizziness

• GI effects (nausea, vomiting, constipation)

Administered in smallest effective dose, as infrequently as possible and titrated to pain control

Administered orally, rectally, SQ, IM, slow IV, slow IV infusion, epidural and intrathecal (IT) injection

Adult:

• Normal oral: 10-30mg 14h as needed

• Normal rectal: 10-20mg q4h as needed

• Normal SQ or IM: 10mg (range 5-20mg) q4h as needed

• Normal IV: 2.5-15mg diluted in 4-5 mL sterile water for injection, slowly injected over 4-5 minutes

Labor anesthesia:

• 10mg SQ or IM