OB-GYN 101
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PTT (Partial Thromboplastin Time)

PTT detects nearly all abnormalities in clotting, due to deficiencies in clotting factors or circulating anticoagulants.

It is frequently used to monitor heparin therapy.

A modification of the test, "Activated PTT," or APTT, is basically the same as PTT, but is slightly more sensitive.

Prolonged PTT is associated with:

  • Liver disease

  • Vitamin K deficiency

  • Anticoagulant (Coumarin, Coumadin, Heparin) therapy

  • DIC

  • Hemophilia

Therapeutic Range (Heparin Therapy)

  • 2-2.5 times the normal

 

 

 

Normal Values*

PTT 30-45 seconds 
APTT 16-25 seconds
Therapeutic Range on oral anticoagulants 2-2.5 times normal

*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another.

 

Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300

OB-GYN 101: Introductory Obstetrics & Gynecology
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