Metronidazole
(Flagyl, MetroGel, MetroGel Vaginal) |
Category:
Description:
Indications:
Contraindications:
Trichomoniasis
infections in the first trimester of pregnancy
Precautions:
-
Pregnancy
category B
-
Use
with caution in patients with organic CNS disease or severe hepatic
dysfunction
-
Use condoms during therapy to avoid re-infection with trichomoniasis
-
Counsel
patient to finish all medication
-
Avoid
using alcohol during therapy and 1-2 days post-therapy to avoid
“disulfiram-type” reaction
-
Will
cause a metallic taste in the mouth
-
Take
with food to avoid GI side effects
-
Will
darken the color of urine
Adverse
Reactions (Side Effects):
-
Seizures
and peripheral neuropathy
-
Gastrointestinal:
anorexia, nausea, diarrhea, cramping, metallic taste
-
Headache
-
Rash
-
Dysuria
and darkened urine
|
Dosage:
-
Administered
orally, topically and IV injection
-
Acute
intestinal amebiasis:
-
Amebic
liver abscess amebiasis:
-
Trichomoniasis
(treat sexual partner(s) also):
-
Anaerobic
bacterial infections:
-
Initial:
15mg/kg infused over one hour
-
Maintenance:
Six hours post loading dose, 75mg/kg (max 4 grams per day) oral or
IV (infused over 1 hour) q6h for 7-10 days
-
Colorectal
surgery prophylaxis:
-
Acne
rosacea
:
-
Bacterial
vaginosis
:
-
Insert
1 applicatorful (5 grams or 37.5mg metronidazole) once or twice a
day for 5 days
-
For
once daily dosing, dose at bedtime
|
|
|
|
The information contained here is an
abbreviated summary. For more detailed and complete information, consult the
manufacturer's product information sheets or standard textbooks
Source: Operational Medicine 2001, Health
Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau
of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington,
D.C., 20372-5300
This information is provided by The Brookside Associates. The Brookside
Associates, LLC. is a private organization, not affiliated with any governmental
agency. The opinions presented here are those of the author and do not
necessarily represent the opinions of the Brookside Associates or the Department
of Defense. The presence of any advertising on these pages does not constitute
an endorsement of that product or service by either the US Department of Defense
or the Brookside Associates. All material presented here is unclassified.
C. 2009, 2014, All Rights Reserved
|
|