Naproxen (Anaprox, Naprosyn)

Category:

  • Analgesic

Description:

  • Nonsteroidal anti-inflammatory drug (NSAID) analgesic

Indications:

  • Inflammatory disease (rheumatoid and osteoarthritis)

  • Mild to moderate pain (orthopedic pain, dental procedures, dysmenorrhea)

  • Fever

  Contraindications:

  • Patients with aspirin or NSAID-induced nasal polyps, bronchospasm or angioedema

  Precautions:

  • Pregnancy Category B

  • Patients may experience potentially serious GI effects, including GI bleeding and ulceration with prolonged, high dose therapy.

  • Avoid use with anticoagulants (warfarin) due to increased bleeding times and potential for GI bleeding and decreased platelet aggregation.

  • Liver function tests should be performed periodically for long-term naproxen use.

  Adverse Reactions (Side Effects):

  • GI effects (nausea, heartburn, dyspepsia, pain)

  • CNS effects (dizziness, headache, nervousness)

  • Tinnitis

Dosage:

Administered orally with food or milk to decrease GI effects

Inflammatory diseases:

  • Adult:  250-500mg bid (275-550mg of naproxen sodium) or 750-1000mg extended release tablets once a day (825 or 1100mg of naproxen sodium)

Pain:

  • Initial dose of 500mg, followed by 250mg q6-8h as needed

 

 

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Approved for public release; Distribution is unlimited.

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks.

Source: Operational Medicine 2001, Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300.

Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300

Operational Medicine
 Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
  January 1, 2001

United States Special Operations Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323

*This web version is provided by The Brookside Associates, LLC.  It contains original contents from the official US Navy NAVMED P-5139, but has been reformatted for web access and includes advertising and links that were not present in the original version. The medical information presented was reviewed and felt to be accurate in 2001. Medical knowledge and practice methods may have changed since that time. Some links may no longer be active. This web version has not been approved by the Department of the Navy or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. The Brookside Associates is a private organization, not affiliated with the United States Department of Defense.

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