Promethazine (Phenergan, Anergan)
Category:
Description:
-
Antihistamine,
antiemetic, sedative, antitussive, antivertigo agent
Indications:
-
Symptomatic
relief of various allergies, active and prophylactic treatment of
motion sickness
-
Preoperative,
postoperative, or obstetric sedation
-
Nausea/vomiting
associated with anesthesia and surgery
-
Adjunct
to analgesic for control of postoperative pain
Contraindications:
Precautions:
-
Pregnancy
category C
-
Acute
asthma, bladder neck obstruction, prostatic hypertrophy
-
Predisposition
to urinary retention, cardiovascular disease, glaucoma
-
Hepatic
function impairment, hypertension, history of peptic ulcer
-
Seizure
disorder, intestinal obstruction
Adverse
Reactions (Side Effects):
-
CNS:
anxiety, confusion, dizziness, drowsiness, EPS reactions, paradoxical
hyperexcitability, euphoria, fatigue, poor coordination
-
CV:
hypotension, palpitations, tachycardia
-
EENT:
Blurred vision, dilated pupils, dry nose, nasal stuffiness, tinnitus
-
GI:
anorexia, cholestatic jaundice, constipation, diarrhea, dry mouth
nausea, vomiting
-
GU:
amenorrhea, dysuria, galactorrhea, gynecomastia, impotence, urinary
retention
-
HEME:
agranulocytosis, hemolytic anemia, thrombocytopenia
-
METAB:
hyperprolactinemia
-
RESP:
chest tightness, increased thick secretions, wheezing
-
SKIN:
photosensitivity, rash, urticaria
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Dosage:
Administered
orally, rectally, intramuscularly, intravenously
-
Adult:
-
Antihistimine:
-
PO/PR
12.5mg 3 times daily and 25mg at bedtime
-
IM/IV
25mg, repeated in 2 hours if necessary, convert to PO as soon
as possible
-
Antiemetic:
-
Motion
sickness:
-
Sedation:
-
Child:
-
Antihistamine:
-
Antiemetic:
-
Motion
sickness:
-
Sedation:
|
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Distribution is unlimited. The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks.
Source: Operational Medicine 2001, Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300.
Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300 |
Operational Medicine
Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
January 1, 2001 |
United States Special Operations
Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323 |
*This web version is provided by The Brookside Associates, LLC. It contains
original contents from the official US Navy NAVMED P-5139, but has been
reformatted for web access and includes advertising and links that were not
present in the original version. The medical information presented was reviewed and felt to be accurate in 2001. Medical knowledge and practice methods may have changed since that time. Some links may no longer be active. This web version has not been approved by the
Department of the Navy or the Department of Defense. The presence of any
advertising on these pages does not constitute an endorsement of that product or
service by either the US Department of Defense or the Brookside Associates. The
Brookside Associates is a private organization, not affiliated with the United
States Department of Defense.
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