Prednisone
(Deltasone, Orasone, Liquid Pred)
Category:
Description:
Indications:
-
Anti-inflammatory
or immunosuppressant agent in the treatment of a variety of diseases
including those of hematologic, allergic, inflammatory, neoplastic,
and autoimmune origin
Contraindications:
Precautions:
-
Pregnancy
category B; compatible with breast feeding
-
Psychosis,
acute glomerulonephritis, amebiasis, cerebral malaria, child < 2
years
-
Elderly,
AIDS, tuberculosis, diabetes mellitus, glaucoma, osteoporosis
-
Ulcerative
colitis, CHF, myasthenia gravis, renal disease, esophagitis
-
Peptic
ulcer, ocular herpes simplex, live virus vaccines, hypertension
Adverse
Reactions (Side Effects):
-
CNS:
depression, headache, mood changes, psychosis, seizures, vertigo
-
CV:
CHF, hypertension, tachycardia, thromboembolism, thrombophlebitis
-
EENT:
blurred vision, cataracts, increased intraocular pressure
-
GI:
abdominal distension, diarrhea, GI hemorrhage (esophagitis, peptic
ulcer) increased appetite, nausea, pancreatitis
-
HEME:
leukocytosis
-
METAB:
Cushingoid syndrome, decreased glucose tolerance, decreased
testosterone levels, growth suppression in children, HPA axis
suppression, hypocalcemia, hypokalemia, metabolic alkalosis, sodium
and fluid retention
-
MS:
aseptic necrosis of femoral and humeral heads, fractures, muscle mass
loss, osteoporosis, weakness
-
SKIN:
acne, bruising, ecchymosis, petechiae, poor wound healing, striae,
suppression of skin test reactions, thin fragile skin
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Dosage:
Administered
orally (tablet, solution)
Drug
interactions:
-
NSAIDs:
increased risk of GI ulceration
-
Antidiabetics:
increased blood glucose in patients with diabetes
-
Salicylates:
enhanced elimination of salicylates; possible subtherapeutic
salicylate concentrations
-
Cyclosporine:
possible increased concentrations of both drugs, seizures
|
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Distribution is unlimited. The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks.
Source: Operational Medicine 2001, Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300.
Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300 |
Operational Medicine
Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
January 1, 2001 |
United States Special Operations
Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323 |
*This web version is provided by The Brookside Associates, LLC. It contains
original contents from the official US Navy NAVMED P-5139, but has been
reformatted for web access and includes advertising and links that were not
present in the original version. The medical information presented was reviewed and felt to be accurate in 2001. Medical knowledge and practice methods may have changed since that time. Some links may no longer be active. This web version has not been approved by the
Department of the Navy or the Department of Defense. The presence of any
advertising on these pages does not constitute an endorsement of that product or
service by either the US Department of Defense or the Brookside Associates. The
Brookside Associates is a private organization, not affiliated with the United
States Department of Defense.
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