Clindamycin
(Cleocin) |
Category:
Description:
Indications:
-
Anaerobic
infections (empyema, lung abscesses, intra-abdominal infections and
absecesses, peritonitis, endometriosis)
-
Streptococci
and Staphylococci infections (serious respiratory and skin infections,
septicemia, osteomyelitis)
-
Pneumococci
infections (respiratory infections)
-
Adjunctive
therapy to surgical treatment of bone and joint infections
-
Dental
procedure prophylaxis
-
Unlabeled
uses:
-
CNS
toxoplasmosis in AIDS patients
-
Pneumocystis
carinii
-
Pelvic
Inflammatory Disease: Chlamydia
trachomatis
-
Bacterial
vaginitis: Gardnerella vaginalis
Contraindications:
-
May
cause a fatal colitis, characterized by severe diarrhea, cramping, and
passage of blood and mucous
-
Not
for treatment of minor bacterial or viral infections
Precautions:
-
Pregnancy
category B
-
Risk
of fatal colitis
-
Does
not adequately diffuse into CSF, therefore not for meningitis therapy
-
Clindamycin
crosses into breast milk
-
Closely
monitor organ system functions when administering to newborns and
infants
-
Monitor
liver/kidney functions and blood counts if administering for prolonged
periods
-
DO
NOT administer as an IV bolus, infuse over 10-60 minutes
Adverse
Reactions (Side Effects):
-
Hypotension
-
CNS:
Headache, mild depression, confusion
-
Gastrointestinal:
diarrhea (2-20%), pseudomembranous colitis (>10% with oral tx),
nausea, vomiting, abdominal pain, esophagitis
-
Jaundice
-
Local
injection site pain, thrombophlebitis
-
Hypersensitivity
reactions: urticaria, erythema multiforme, generalized morbilliform-like
rash
-
Take
each dose with a full glass of water (decreases esophageal iritiation)
-
May
be taken without regard for meals
-
Complete
full course of therapy
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Dosage:
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The information contained here is an
abbreviated summary. For more detailed and complete information, consult the
manufacturer's product information sheets or standard textbooks
Source: Operational Medicine 2001, Health
Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau
of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington,
D.C., 20372-5300
This information is provided by The Brookside Associates. The Brookside
Associates, LLC. is a private organization, not affiliated with any governmental
agency. The opinions presented here are those of the author and do not
necessarily represent the opinions of the Brookside Associates or the Department
of Defense. The presence of any advertising on these pages does not constitute
an endorsement of that product or service by either the US Department of Defense
or the Brookside Associates. All material presented here is unclassified.
C. 2009, 2014, All Rights Reserved
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