Metaraminol
(Aramine) |
Category:
Description:
Indications:
-
Acute
hypotensive states associated with spinal anesthesia, hemorrhage,
reactions to medications, surgical complications
-
Shock
associated with brain damage resulting from trauma or tumor
-
“Probably
effective” in hypotension due to cardiogenic shock or septicemia
Contraindications:
Precautions:
-
Pregnancy
category D
-
Prolonged
administration, heart disease, thyroid disease, hypertension, diabetes
-
Cirrhosis,
extravasation (phentolamine is antidote), history of malaria
-
Sulfite
sensitivity
Adverse
Reactions (Side Effects):
-
CNS:
apprehension, dizziness, headache, tremors
-
CV:
cardiac arrest, flushing, hypertension, hypotension (following
cessation), palpitation, sinus tachycardia, ventricular tachycardia,
other dysrhymias
-
GI:
nausea
-
SKIN:
extravasation (abscess, necrosis, sloughing), sweating
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Dosage:
Administered
subcutaneously, intramuscularly, intravenously
-
Adult:
-
SC/IM
2-10mg
-
IV
INF dilute 15-500mg in 500mg D5W or NS, administer at a rate
adjusted to maintain desired blood pressure
-
IV
0.5-5mg as a single dose in severe shock, follow with IV INF
-
Child:
-
SC/IM
0.1 mg/kg or 3 mg/meter square
-
IV
INF 0.4 mg/kg or 12 mg/meter square, diluted and administered at a
rate adjusted to maintain desired blood pressure
-
IV
0.01 mg/kg or 0.3 mg/meter square as a single dose in severe
shock, follow with IV INF
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The information contained here is an
abbreviated summary. For more detailed and complete information, consult the
manufacturer's product information sheets or standard textbooks
Source: Operational Medicine 2001, Health
Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau
of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington,
D.C., 20372-5300
This information is provided by The Brookside Associates. The Brookside
Associates, LLC. is a private organization, not affiliated with any governmental
agency. The opinions presented here are those of the author and do not
necessarily represent the opinions of the Brookside Associates or the Department
of Defense. The presence of any advertising on these pages does not constitute
an endorsement of that product or service by either the US Department of Defense
or the Brookside Associates. All material presented here is unclassified.
C. 2009, 2014, All Rights Reserved
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