Kanamycin
injection (Kantrex) |
Category:
Description:
Indications:
-
Serious
infections (P. aeruginosa,
Proteus species, E. coli,
Klebsiella species,
Enterobacter species,
Serratia species, Citrobacter species, Staphylococcus species)
-
Bacterial
neonatal sepsis
-
Bacterial
septicemia
-
Serious
bacterial infections of the CNS (meningitis)
-
Urinary
tract, respiratory tract, skin, bone and soft tissue (including burns)
infections
-
Gram-negative
infections
-
Emperic
therapy for unknown serious infections
-
Unlabeled
use:
Contraindications:
Precautions:
-
Pregnancy
category D
-
May
cause nephrotoxicity, therefore closely monitor renal function,
especially in elderly patients.
-
May
cause ototoxicity, therefore monitor hearing
-
Monitor
peak and trough serum concentrations
-
In
patients with extensive burns, altered pharmacokinetics may alter
serum concentrations.
-
May
produce hypomagnesemia, especially if poor or restricted diet.
-
Aminoglycosides
have neuromuscular blockade activity with a curare-like effect. Monitor patient’s neuromuscular function, especially in
patients with myasthenia gravis, parkinsonism or infant botulism.
-
Administer
over 30-60 minute infusion
Adverse
Reactions (Side Effects):
-
Renal:
oliguria, proteinuria, increased creatinine and BUN
-
Miscellaneous:
apnea
-
Pain
at injection site
-
Granular
casts
-
“Malabsorption
syndrome” characterized by increase in fetal fat, decrease in serum
carotene and fall in xylose absorption
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Dosage:
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The information contained here is an
abbreviated summary. For more detailed and complete information, consult the
manufacturer's product information sheets or standard textbooks
Source: Operational Medicine 2001, Health
Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau
of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington,
D.C., 20372-5300
This information is provided by The Brookside Associates. The Brookside
Associates, LLC. is a private organization, not affiliated with any governmental
agency. The opinions presented here are those of the author and do not
necessarily represent the opinions of the Brookside Associates or the Department
of Defense. The presence of any advertising on these pages does not constitute
an endorsement of that product or service by either the US Department of Defense
or the Brookside Associates. All material presented here is unclassified.
C. 2009, 2014, All Rights Reserved
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