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Fluoride Sodium (Luride, Pediaflor, Pharmaflur, Gel-Kam, various)

Category:

  • Miscellaneous

Description:

  • Anti-dental caries agent

Indications:

  • Prevention of dental caries

Contraindications:

  • Hypersensitivity

Precautions:

  • Pregnancy and lactation: Administration from 3rd-9th month of gestation safe (no information on teratogenicity); small amounts excreted into breast milk, inadequate therapeutically due to small amount of excretion and complexation with calcium

  • Drinking water >0.7 ppm fluoride

Adverse Reactions (Side Effects):

  • EENT: watery eyes

  • GI: black tarry stools, constipation, diarrhea, discoloration of teeth, hematemesis, increased salivation, loss of appetite, nausea, stomatitis, weight loss

  • METAB: hypocalcemia

  • MS: articular and juxta-articular pain, osteomalacia, stress fractures, tetany

  • RESP: decreased respiration, respiratory arrest

Dosage:

Administered orally (drops, lozenges, tablets, rinse, gel)

NOTE: 2.2mg sodium fluoride equivalent to 1mg fluoride ion

  • Adult and child >12 years: 

    • Dental rinse: TOP apply 10ml 0.2% solution every day after brushing teeth, rinse mouth for >1 minute with solution then expectorate

  • Child:   

    • Brush-on-gel: After brushing with toothpaste, >6 years apply thin ribbon of gel to teeth with toothbrush for at least 1 minute at bedtime, expectorate gel and rinse mouth thoroughly

    • Dental rinse: TOP 5ml 0.2% solution daily after brushing teeth, rinse mouth for >1 minute with solution then expectorate

    • Gel drops: >6 years: use applicators supplied by dentist; apply 4-8 drops to inner surface of applicator, spread evenly with tip of bottle; place applicator over upper and lower teeth and bite down gently for 6 minutes; remove and rinse mouth

  • Systemic protection from periodontal disease: PO in areas where fluoride content of drinking water < 0.3 ppm, <2years 0.25mg fluoride daily, 2-3 years 0.5mg daily, 3-12 years 1mg daily; in areas where fluoride content of drinking water is 0.3-0.7 ppm, <2 years 0.125mg fluoride daily, 2-3 years 0.25mg daily, 3-14 years 0.25-0.75mg daily

 


The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks

Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300

This information is provided by The Brookside Associates.  The Brookside Associates, LLC. is a private organization, not affiliated with any governmental agency. The opinions presented here are those of the author and do not necessarily represent the opinions of the Brookside Associates or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. All material presented here is unclassified.

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