Clarithromycin
(Biaxin) |
Category:
Description:
Indications:
-
Pharyngitis/Tonsillitis
(S. pyogenes)
-
Acute
maxilliary sinusitis (H.
influenzae, M. catarrhalis, S. pneumoniae)
-
Acute
bacterial exacerbation of chronic bronchitis (H.
influenzae, M. catarrhalis, S. pneumoniae)
-
Pneumonia
(Chlamydia pneumoniae, Strep.
pneumoniae, Mycoplasma pneumoniae)
-
Skin
infections (S. aureus, S.
pyogenes)
-
Disseminated
mycobacterial infections (Mycoplasma
avium and intracellulare)
-
Mycobacterium
Avium Complex prophylaxis
-
Helicobacter pylori therapy (double and triple)
-
Acute
otitis media (H. influenzae, M.
catarrhalis, S. pneumoniae)
Contraindications:
Precautions:
-
Pregnancy
category B
-
Use
alternate form of birth control (disrupts absorption of oral
contraceptives and renders them inactive)
-
Counsel
patient to finish all medication to prevent development of resistance
-
Do
not use with aluminum or magnesium-containing antacids
-
Do
not use with cisapride (ventricular arrythmias w/macrolides)
Adverse
Reactions (Side Effects):
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Dosage:
-
Administered
orally (tablets, granules for oral suspension)
-
Adult:
-
Pharyngitis/Tonsillitis:
-
Maxilliary
sinusitis:
-
Chronic bronchitis & pneumonia (S.
pneumoniae/M. catarrhalis):
-
Chronic
bronchitis (H. influenzae):
-
Uncomplicated
skin infections:
-
MAC:
-
H.
pylori treatment:
-
double
tx: 500mg tid plus omeprazole 40mg qam days 1-14, then omeprazole
20mg qam days 15-28
-
triple
tx: 500mg tid plus ranitidine bismuth citrate 400mg bid days 1-14,
then ranitidine bismuth citrate 400mg bid days 15-28
-
Child:
-
15mg/kg/day
divided every 12 hours for 10 days
-
For
oral suspension: empty
stomach, refrigerate, shake well, good for 14 days only
-
MAC:
7.5mg/kg/day up to 500mg twice a day
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The information contained here is an
abbreviated summary. For more detailed and complete information, consult the
manufacturer's product information sheets or standard textbooks
Source: Operational Medicine 2001, Health
Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau
of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington,
D.C., 20372-5300
This information is provided by The Brookside Associates. The Brookside
Associates, LLC. is a private organization, not affiliated with any governmental
agency. The opinions presented here are those of the author and do not
necessarily represent the opinions of the Brookside Associates or the Department
of Defense. The presence of any advertising on these pages does not constitute
an endorsement of that product or service by either the US Department of Defense
or the Brookside Associates. All material presented here is unclassified.
C. 2009, 2014, All Rights Reserved
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