Nalbuphine (Nubain)

Category:

  • Analgesic

Description:

  • Synthetic partial opiate agonist analgesic

Indications:

  • Moderate to severe pain associated with chronic conditions (cancer, othropedic pain)

  • Moderate to severe pain associated with surgical procedures .

Contraindications:

  • Patients with impaired respiratory function.  

Precautions:

  • Pregnancy Category C

  • Patients will experience CNS effects of drowsiness and dizziness, therefore use caution with motor vehicle operation or other hazardous tasks.

  • Avoid prolonged, sustained usage to decrease addiction potential.

  • Use with caution with other CNS depressive medications.

Adverse Reactions (Side Effects):

  • Sedation

  • Dizziness

  • GI effects (nausea, vomiting, dry mouth)

Dosage:

Administered in smallest effective dose, as infrequently as possible and titrated to pain control

Administered SQ, IM or IV

Adult (non-opiate tolerant):

  • Normal: 10mg (in 70kg patient), then repeated q3-6h as needed

  • Maximum single dose: 20mg

  • Maximum daily dose: 160mg

Adult (opiate tolerant):

  • Administer 25% of usual nalbuphine dose

Anesthesia adjunct:

  • 0.3-3mg/kg given IV over 10-15 minutes, then 0.25-0.5mg/kg IV as needed

 

 

 

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Approved for public release; Distribution is unlimited.

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks.

Source: Operational Medicine 2001, Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300.

Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300

Operational Medicine
 Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
  January 1, 2001

United States Special Operations Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323

*This web version is provided by The Brookside Associates, LLC.  It contains original contents from the official US Navy NAVMED P-5139, but has been reformatted for web access and includes advertising and links that were not present in the original version. The medical information presented was reviewed and felt to be accurate in 2001. Medical knowledge and practice methods may have changed since that time. Some links may no longer be active. This web version has not been approved by the Department of the Navy or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. The Brookside Associates is a private organization, not affiliated with the United States Department of Defense.

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