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Progesterone

Progesterone is a female hormone, produced primarily in the ovary, primarily during the second half ("luteal phase") of the menstrual cycle. Men also produce progesterone, but only very small amounts.

Shortly after ovulation, progesterone levels rise quickly and remain elevated for about 10 days. 

  • If pregnancy occurs, the progesterone levels remain elevated. 
  • If pregnancy does not occur, then progesterone levels fall, provoking a menstrual flow.

Progesterone levels are sometimes used to evaluate a possible ectopic pregnancy:

  • If progesterone > 25, ectopic pregnancy is very unlikely
  • When less than 25, the results are not conclusive either way.

Elevations found in:

  • Pregnancy
  • Second half of the menstrual cycle
  • Congenital adrenal hyperplasia
  • Some hormone-producing tumors of the ovary

Decreases found in:

  • Polycystic Ovary Syndrome (PCO, Stein-Levinthal Syndrome)
  • Amenorrhea-Galactorrhea Syndrome
  • Luteal phase defects
  • Menopause
  • Ovarian failure

Normal Values*

Men < 1.0 ng/ml

Women 
(Proliferative Phase)

< 1.5 ng/ml
Women
(Luteal Phase)
3-20 ng/ml

*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another.


 

 

Approved for public release; Distribution is unlimited.
The listing of any non-Federal product in this CD is not an endorsement of the product itself, but simply an acknowledgement of the source. 

Bureau of Medicine and Surgery
Department of the Navy
2300 E Street NW
Washington, D.C
20372-5300

Operational Medicine
 Health Care in Military Settings
CAPT Michael John Hughey, MC, USNR
NAVMED P-5139
  January 1, 2001

United States Special Operations Command
7701 Tampa Point Blvd.
MacDill AFB, Florida
33621-5323

*This web version is provided by The Brookside Associates Medical Education Division.  It contains original contents from the official US Navy NAVMED P-5139, but has been reformatted for web access and includes advertising and links that were not present in the original version. This web version has not been approved by the Department of the Navy or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. The Brookside Associates is a private organization, not affiliated with the United States Department of Defense.

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