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Orphenadrine (Norflex, Banflex, Orfro, Orpenate)

Category:

  • Skeletal Muscle Relaxant

Description:

  • Skeletal Muscle Relaxant

Indications:

  • Painful acute musculoskeletal conditions

  • Quinine-resistant leg cramps (non FDA approved)

Contraindications:

  • Glaucoma, pyloric or duodenal obstruction, stenosing peptic ulcer

  • Prostatic hypertrophy, obstruction of bladder neck, cardiospasm, myasthenia gravis

Precautions:

  • Pregnancy category C

  • Children, cardiac decompensation

  • Coronary insufficiency, cardiac dysrhythmia

  • Tachycardia, sulfite sensitivity

Adverse Reactions (Side Effects):

  • CNS: agitation, confusion, dizziness, drowsiness, hallucinations, headache, lightheadedness, tremor, weakness

  • CV: palpitation, tachycardia, transient syncope

  • EENT: blurred vision, increased ocular tension, pupil dilation

  • GI: constipation, dry mouth, gastric irritation, nausea, vomiting

  • GU: urinary hesitancy, urinary retention

  • HEME: aplastic anemia (rare)

  • SKIN: urticaria and other dermatoses

 

 

Dosage:

Administered orally, intramuscularly, intravenously

  • Adult:   PO 100mg 2 times daily; IM/IV 60mg, may repeat every 12 hours as needed

 

 

 

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks.

Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300

OB-GYN 101: Introductory Obstetrics & Gynecology
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