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Fluoride Sodium (Luride, Pediaflor, Pharmaflur, Gel-Kam, various)

Category:

  • Miscellaneous

Description:

  • Anti-dental caries agent

Indications:

  • Prevention of dental caries

Contraindications:

  • Hypersensitivity

Precautions:

  • Pregnancy and lactation: Administration from 3rd-9th month of gestation safe (no information on teratogenicity); small amounts excreted into breast milk, inadequate therapeutically due to small amount of excretion and complexation with calcium

  • Drinking water >0.7 ppm fluoride

Adverse Reactions (Side Effects):

  • EENT: watery eyes

  • GI: black tarry stools, constipation, diarrhea, discoloration of teeth, hematemesis, increased salivation, loss of appetite, nausea, stomatitis, weight loss

  • METAB: hypocalcemia

  • MS: articular and juxta-articular pain, osteomalacia, stress fractures, tetany

  • RESP: decreased respiration, respiratory arrest

 

 

 

Dosage:

Administered orally (drops, lozenges, tablets, rinse, gel)

NOTE: 2.2mg sodium fluoride equivalent to 1mg fluoride ion

  • Adult and child >12 years: 

    • Dental rinse: TOP apply 10ml 0.2% solution every day after brushing teeth, rinse mouth for >1 minute with solution then expectorate

  • Child:   

    • Brush-on-gel: After brushing with toothpaste, >6 years apply thin ribbon of gel to teeth with toothbrush for at least 1 minute at bedtime, expectorate gel and rinse mouth thoroughly

    • Dental rinse: TOP 5ml 0.2% solution daily after brushing teeth, rinse mouth for >1 minute with solution then expectorate

    • Gel drops: >6 years: use applicators supplied by dentist; apply 4-8 drops to inner surface of applicator, spread evenly with tip of bottle; place applicator over upper and lower teeth and bite down gently for 6 minutes; remove and rinse mouth

  • Systemic protection from periodontal disease: PO in areas where fluoride content of drinking water < 0.3 ppm, <2years 0.25mg fluoride daily, 2-3 years 0.5mg daily, 3-12 years 1mg daily; in areas where fluoride content of drinking water is 0.3-0.7 ppm, <2 years 0.125mg fluoride daily, 2-3 years 0.25mg daily, 3-14 years 0.25-0.75mg daily

 

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks. Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300

OB-GYN 101: Introductory Obstetrics & Gynecology
© 2003, 2004, 2005, 2008 Medical Education Division, Brookside Associates, Ltd.
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