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 Proposed 2001 Terminology

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SPECIMEN TYPE: Indicate conventional smear (Pap smear) vs. liquid based vs. other

SPECIMEN ADEQUACY

  • Satisfactory for evaluation (describe presence or absence of endocervical/transformation zone component and any other quality indicators, e.g., partially obscuring blood, inflammation, etc.)

  • Unsatisfactory for evaluation ... (specify reason)

    • Specimen rejected/not processed (specify reason)

    • Specimen processed and examined, but unsatisfactory for evaluation of epithelial abnormality because of (specify reason)

GENERAL CATEGORIZATION (optional)

  • Negative for Intraepithelial Lesion or Malignancy

  • Epithelial Cell Abnormality: See Interpretation/Result (specify ‘squamous’ or ‘glandular’ as appropriate)

  • Other: See Interpretation/Result (e.g. endometrial cells in a woman ³ 40 years of age)

AUTOMATED REVIEW

    If case examined by automated device, specify device and result.

ANCILLARY TESTING

    Provide a brief description of the test methods and report the result so that it is easily understood by the clinician.

INTERPRETATION/RESULT

    NEGATIVE FOR INTRAEPITHELIAL LESION OR MALIGNANCY (when there is no cellular evidence of neoplasia, state this in the General Categorization above and/or in the Interpretation/Result section of the report, whether or not there are organisms or other non-neoplastic findings)

      ORGANISMS:

      • Trichomonas vaginalis

      • Fungal organisms morphologically consistent with Candida spp

      • Shift in flora suggestive of bacterial vaginosis

      • Bacteria morphologically consistent with Actinomyces spp.

      • Cellular changes consistent with Herpes simplex virus

      OTHER NON NEOPLASTIC FINDINGS (Optional to report; list not inclusive):

      • Reactive cellular changes associated with

        • inflammation (includes typical repair)

        • radiation

        • intrauterine contraceptive device (IUD)

      • Glandular cells status post hysterectomy

      • Atrophy

    OTHER

    • Endometrial cells (in a woman ³ 40 years of age)
      (Specify if ‘negative for squamous intraepithelial lesion’)

    EPITHELIAL CELL ABNORMALITIES

      SQUAMOUS CELL

      • Atypical squamous cells

        • of undetermined significance (ASC-US)

        • cannot exclude HSIL (ASC-H)

      • Low grade squamous intraepithelial lesion (LSIL)
                  encompassing: HPV/mild dysplasia/CIN 1

      • High grade squamous intraepithelial lesion (HSIL)
                  encompassing: moderate and severe dysplasia, CIS/CIN 2 and CIN 3

        • with features suspicious for invasion (if invasion is suspected)

      • Squamous cell carcinoma

      GLANDULAR CELL

      • Atypical

        • endocervical cells (NOS or specify in comments)

        • endometrial cells (NOS or specify in comments)

        • glandular cells (NOS or specify in comments)

      • Atypical

        • endocervical cells, favor neoplastic

        • glandular cells, favor neoplastic

      • Endocervical adenocarcinoma in situ

      • Adenocarcinoma

        • endocervical

        • endometrial

        • extrauterine

        • not otherwise specified (NOS)

    OTHER MALIGNANT NEOPLASMS: (specify)

EDUCATIONAL NOTES AND SUGGESTIONS (optional)

    Suggestions should be concise and consistent with clinical follow-up guidelines published by professional organizations (references to relevant publications may be included).