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Progesterone (Prometrium®)

Category:

  • Hormonal

Description:

  • Progesterone hormone (pelletized natural progesterone)

Indications:

  • Abnormal uterine bleeding (due to hormonal imbalance in the absence of organic pathology)

  • Secondary amenorrhea

Contraindications:

  • Current or history of thrombophlebitis, thromboembolic disorders, and cerebral apoplexy

  • Liver impairment, known or suspected malignancy of the breast or genitalia

  • Undiagnosed genital bleeding

  • Missed abortion

  • Use as a pregnancy diagnostic test

Precautions:

  • Pregnancy category B

  • Contains peanut oil, not appropriate for those with peanut allergies.

  • Use with caution in pregnant or nursing mothers

  • Use with caution in patients with diabetes, epilepsy, migraine, asthma, cardiac or renal dysfunction, or history of depression.

Adverse Reactions (Side Effects):

  • Dizziness

  • Breast pain

  • Headache

  • Abdominal pain

  • Fatigue

Dosage:

Administered orally

  • Prevention of endometrial hyperplasia

    • Single daily dose in the evening, 200 mg orally for 12 days sequentially per 28 day cycle

  • Secondary amenorrhea: 

    • Single daily dose of 400 mg in the evening for 10 days.

 


The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks

Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300

This information is provided by The Brookside Associates.  The Brookside Associates, LLC. is a private organization, not affiliated with any governmental agency. The opinions presented here are those of the author and do not necessarily represent the opinions of the Brookside Associates or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. All material presented here is unclassified.

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