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Orphenadrine (Norflex, Banflex, Orfro, Orpenate)

Category:

  • Skeletal Muscle Relaxant

Description:

  • Skeletal Muscle Relaxant

Indications:

  • Painful acute musculoskeletal conditions

  • Quinine-resistant leg cramps (non FDA approved)

Contraindications:

  • Glaucoma, pyloric or duodenal obstruction, stenosing peptic ulcer

  • Prostatic hypertrophy, obstruction of bladder neck, cardiospasm, myasthenia gravis

Precautions:

  • Pregnancy category C

  • Children, cardiac decompensation

  • Coronary insufficiency, cardiac dysrhythmia

  • Tachycardia, sulfite sensitivity

Adverse Reactions (Side Effects):

  • CNS: agitation, confusion, dizziness, drowsiness, hallucinations, headache, lightheadedness, tremor, weakness

  • CV: palpitation, tachycardia, transient syncope

  • EENT: blurred vision, increased ocular tension, pupil dilation

  • GI: constipation, dry mouth, gastric irritation, nausea, vomiting

  • GU: urinary hesitancy, urinary retention

  • HEME: aplastic anemia (rare)

  • SKIN: urticaria and other dermatoses

Dosage:

Administered orally, intramuscularly, intravenously

  • Adult:   PO 100mg 2 times daily; IM/IV 60mg, may repeat every 12 hours as needed

 

 

 

 


The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks

Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300

This information is provided by The Brookside Associates.  The Brookside Associates, LLC. is a private organization, not affiliated with any governmental agency. The opinions presented here are those of the author and do not necessarily represent the opinions of the Brookside Associates or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. All material presented here is unclassified.

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