Category:

• Nervous System

Description:

• Mydriatic, cycloplegic, ophthalmic anticholinergic

Indications:

• Cycloplegic refraction

• Mydriasis

Contraindications:

• Infants < 3 months

• Narrow-angle glaucoma

Precautions:

• Pregnancy category C

• Elderly (more risk of increased intraocular pressure)

• Infants, children with spastic paralysis or brain damage

Adverse Reactions (Side Effects):

• CNS: ataxia, behavior disturbances, confusion, disorientation, failure to recognize people, grand mal seizures, hallucinations, irritability, psychotic reaction, somnolence

• CV: tachycardia

• EENT: blurred vision, conjunctivitis, eye dryness, photophobia, increased intraoculary pressure, burning upon instillation

• GI: abdominal discomfort/distention, dry mouth, vomiting

• MISC: bladder distension, dry skin, fever, flushing, irregular pulse, respiratory depression

Dosage:

Administered as an ophthalmic solution

• Adult:            

  • OPHTH SOL 1 drop of a 0.5%-2% solution, then 1 drop in 5 minutes if necessary

• Child (> age 6):  

  • OPHTH SOL 1 drop of a 0.5%-2% solution, then 1 drop of a 0.5%-1% solution if necessary