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Serum proteins are primarily albumin (50-60%, produced by the liver), but also include globulins, and other proteins. 

Serum proteins:

  • Maintain water balance in the blood through osmotic pressure
  • Transport blood components and nutritional elements
  • Help the immune system
  • Help with coagulation

Increased protein levels may be seen in:

  • Dehydration
  • Liver disease
  • Tuberculosis
  • Lupus
  • Collagen vascular disease
  • Some cancers
  • Hemoconcentration

Decreased protein levels may be seen in:

  • Liver disease (decreased production)
  • Malnutrition (decreased production)
  • Diarrhea (increased loss)
  • Renal disease (increased loss)
  • Severe burns (increased loss)
  • Hemorrhage (increased loss)
  • Pregnancy (dilutional)

Normal Values*

Men-Women 3.8-5.0 g/dl
Pregnancy 3.0-4.0 g/dl

*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another.

Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300  

Military Obstetrics & Gynecology
© 2003, 2004, 2005, 2006 Medical Education Division, Brookside Associates, Ltd.
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This information is provided by The Brookside Associates.  The Brookside Associates, LLC. is a private organization, not affiliated with any governmental agency. The opinions presented here are those of the author and do not necessarily represent the opinions of the Brookside Associates or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. All material presented here is unclassified.

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