ANA (Antinuclear Antibodies)

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ANA (Antinuclear Antibodies)

Antinuclear Antibodies are globulins that can react with the nuclei of cells. There is a connection between the presence of these antibodies and the presence of various auto-immune diseases.

Most individuals with.Lupus, Scleroderma, and Rheumatoid Arthritis will have a positive ANA test.
About a third of individuals with Sjoegren's Disease, Dermatomyositis and Polyarteritis will be positive for ANA.
Some normal individuals are positive for ANA
Some apparently normal individuals who are positive for ANA will, later in life, develop an auto-immune disease.
A negative ANA is strong evidence against auto-immune disease being present.

Normal Values*

Titer

1:10 (1:20 in some labs)

*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another.

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks

Source: Operational Medicine 2001, Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300

This information is provided by The Brookside Associates. The Brookside Associates, LLC. is a private organization, not affiliated with any governmental agency. The opinions presented here are those of the author and do not necessarily represent the opinions of the Brookside Associates or the Department of Defense. The presence of any advertising on these pages does not constitute an endorsement of that product or service by either the US Department of Defense or the Brookside Associates. All material presented here is unclassified.

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